GLOHRA Research Projects

The German Alliance for Global Health Research (GLOHRA) is a proponent for interdisciplinary and collaborative global health research. Addressing the complex challenges we face today – neglected tropical diseases and antibiotic resistance, but also mental illness and diabetes together with achieving universal health coverage and the human right to health – requires research approaches that defy traditional boundaries. GLOHRA seeks to foster exchange and forge new mechanisms of cooperation across institutions, disciplines, sectors and countries.

BMBF has agreed to fund the following projects selected by GLOHRA:

Diarrhea, fiber and colon cancer: Environmental contributions to low colon cancer risk in sub-Saharan Africa

Global Health Fellowship

Applicant: Dr. Sören Ocvirk, German Institute of Human Nutrition Potsdam-Rehbrücke

In a nutshell: This study proposes a novel mechanism for colorectal cancer (CRC) prevention. The team will examine a population with low risk for colon cancer, individuals in sub-Saharan Africa, with special attention to the role of dietary fiber consumption and pathogenic intestinal bacteria. Insights could have implication for targeted prevention of CRC in high-risk groups.

Planned Duration: May 2021 – April 2023

Research Areas: Biomedical Sciences, Public Health

MeasureGender: Measuring gender-based discrimination to better understand maternal mortality

Interdisciplinary Pilot Project

Applicants: PD. Dr. med. Wilm Quentin, Technische Universität Berlin and Prof. Dr. Manuela De Allegri, Heidelberg University

In a nutshell: Drawing on sociological and medical perspectives, this project aims to develop a culturally adapted tool for measuring gender-based discrimination. The team hopes that the tool, Measure-Gender, developed via field research and interviews, can be used in future surveys to improve our understanding of the relationship between gender-based discrimination and maternal health outcomes.

Planned Duration: May 2021 - April 2022

Research Areas: Biomedical Sciences, Social Sciences and Humanities

IMPEDE-CVD: Human centered design to adapt and inform an integrated chronic disease management program

Cross-sector Project

Applicants: Prof. Dr. Felix Knauf, Charité - Universitätsmedizin Berlin; Dr. Shannon McMahon-Rössle, Prof. Dr. Dr. Till Bärnighausen, both Universitätsklinikum Heidelberg; Dr. Julius Emmrich, Dr. Samuel Knauss, both mTOMADY gGmbh

In a nutshell: Research meets implementation in this digital health project in Uganda. The team aims to assess the feasibility, acceptability, perception, and usefulness of a mobile phone-based program, IMPEDE-CVD, to detect and manage cardiovascular disease in Uganda. This will ideally improve the detection and management of chronic diseases and reduce their financial burden in resource-poor communities.

Planned Duration: May 2021 - April 2023

Research Areas: Biomedical Sciences, Public Health, Engineering and Other Sciences

Vaccines and helminths: The impact of helminth infections on vaccine outcomes in humans – a systematic literature review

Interdisciplinary Pilot Project

Applicants: Prof. Dr. Clarissa Prazeres da Costa, Prof. Dr. Stefanie Klug, Technische Universität München; Dr. Meral Esen, Eberhard Karls Universität Tübingen

In a nutshell: Reflecting on the pivotal role of vaccines in prevention and control of infectious diseases, this interdisciplinary project seeks to systematically review and analyze the impact of helminth infections  on the immune response to and efficacy of vaccines. Insights from this project will lead to the generation of knowledge-translation resources to inform clinical and public health practice guidelines, set the basis for the design of new studies investigating new vaccination strategies and eventually formulate scientific consensus statements.

Research Areas: Biomedical Sciences, Public Health

Planned Duration: June 2021 - November 2022